References
Neu HC The development of macrolides: clarithromycin in perspective. Journal of Antimicrobial Chemotherapy 1991, 27, Supplement A: 1–9.
Fernandes PB, Ramer N, Rode RA, Freiberg L Bioassay for A-56268 (TE-031) and identification of its major metabolite 14-hydroxy-6-0-methyl erythromycin. European Journal of Clinical Microbiology and Infectious Diseases 1988, 7: 73–76.
Dabernat H, Delmas G, Seguy M, Fourtillan JB, Girault J, Lareng MB The activity of clarithromycin and its 14-hydroxy metabolite againstHaemophilus influenzae, determined by in vitro and serum bactericidal tests. Journal of Antimicrobial Chemotherapy 1991, 27, Supplement A: 19–30.
Hardy DJ, Swanson RN, Rode RA, Marsh K, Shipkowitz NL, Clement JJ Enhancement of the in vitro and in vivo activities of clarithromycin againstHaemophilus influenzae by 14-hydroxy-clarithromycin, its major metabolite in humans. Antimicrobial Agents and Chemotherapy 1990, 34: 1407–1413.
Logan MN, Ashby JP, Andrews JM, Wise R The in vitro activity and disc susceptibility testing of clarithromycin and its 14-hydroxy metabolite. Journal of Antimicrobial Chemotherapy 1991, 27: 161–170.
Powell M, Chen HY, Weinhardt B, Williams JD In vitro activity of clarithromycin and its 14-hydroxy metabolite (A-62671) againstHaemophilus influenzae. Journal of Antimicrobial Chemotherapy 1991, 27: 694–696.
National Committee for Clinical Laboratory Standards Performance standards for antimicrobial disk susceptibility tests. Approved standard M2-A4 (4th edition). NCCLS, Villanova, PA, 1990.
National Committee for Clinical Laboratory Standards Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A2 (2nd edition). NCCLS, Villanova, PA, 1990.
Barry AL, Fernandes PB, Jorgensen JH, Thornsberry G, Hardy DJ, Jones RN Variability of clarithromycin and erythromycin susceptibility tests withHaemophilus influenzae in four different broth media and correlation with the standard disk diffusion test. Journal of Clinical Microbiology 1988, 26: 2415–2420.
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Barry, A.L., Fuchs, P.C. & Pfaller, M.A. Susceptibility ofHaemophilus influenzae to clarithromycin alone and in combination with its 14-hydroxy metabolite. Eur. J. Clin. Microbiol. Infect. Dis. 10, 1080–1081 (1991). https://doi.org/10.1007/BF01984936
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DOI: https://doi.org/10.1007/BF01984936