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, Volume 32, Issue 1–2, pp 96–97 | Cite as

Does allopurinol prevent superoxide radical production by xanthine oxidase (XOD)?

  • A. Haberland
  • H. Luther
  • I. Schimke
Papers Given at the 12th European Workshop on Inflammation, Halle, Germany, May 30–31, 1990 Free Communications


Superoxide Xanthine Xanthine Oxidase Allopurinol Radical Production 


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    E. Tubaro, B. Lotti, C. Santiangeli and G. Cavallo,Xanthine oxidase: an enzyme playing a role in the killing mechanism of polymorphonuclear leucocytes. Biochem. Pharmacol.29, 3018–3020 (1980).CrossRefPubMedGoogle Scholar
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    W. H. Bannister and J. O. Bannister,Biological and clinical aspects of superoxide and superoxide dismutase. North Holland, Inc., New York-Amsterdam-Oxford, 1980.Google Scholar
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    S. W. Werns, M. J. Shea and S. E. Mitsos,Reduction of the size infarction by allopurinol in the ischemic-reperfused canine heart. Circulation73, 518–524 (1986).PubMedGoogle Scholar
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    K. A. Reimer and R. B. Jennings,Failure of xanthine oxidase inhibitor allopurinol to limit infarct size after ischemia and reperfusion in dogs. Circulation71, 1069–1075 (1985).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1991

Authors and Affiliations

  • A. Haberland
    • 1
  • H. Luther
    • 2
  • I. Schimke
    • 1
  1. 1.Institute of Pathological and Clinical BiochemistryCharité-HospitalBerlin
  2. 2.Department BiochemistryResearch Institute of Lung Diseases and TuberculosisBerlin-Buch

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