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, Volume 17, Issue 3–4, pp 392–394 | Cite as

Oxidation of suitable drugs by horseradish peroxidase/hydrogen peroxide results in the oxygenation of arachidonic acid to form hydroperoxyeicosatetraenoic acids in a reverse co-oxidation process

  • J. Baumann
  • I. Just
  • G. Wurm
General Inflammation Studies

Keywords

Peroxide Arachidonic Acid Suitable Drug Hydroperoxyeicosatetraenoic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. [1]
    L.J. Marnett, P. Wlodawer andB. Samuelsson,Light emission during the action of prostaglandin synthetase, Biochem. Biophys. Res. Commun.60, 1286–1294 (1974).CrossRefPubMedGoogle Scholar
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    B. Bösterling andJ.R. Trudell,Production of 5- and 15-hydroperoxyeicosatetraenoic acid from arachidonic acid by halothane free radicals generated by UV-irradiation, Anesthesiology60, 209–213 (1984).PubMedGoogle Scholar
  3. [3]
    P.D. Josephy, T.E. Eling andR.P. Mason, Oxidation of p-aminophenol catalyzed by horseradish peroxidase and prostaglandin synthase. Mol. Pharm.23, 461–466 (1983).Google Scholar
  4. [4]
    I. Knippel, J. Baumann, F. v. Bruchhausen andG. Wurm,Interactions of sulfhydryl agents and soybean lipoxygenase inhibitors, Biochem. Pharmac.30, 1677–1684 (1981).CrossRefGoogle Scholar
  5. [5]
    C.W. Garner,Peroxidation of free and esterified fatty acids by horseradish peroxidase, Lipids19, 863–868 (1984).Google Scholar

Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • J. Baumann
    • 1
  • I. Just
    • 1
  • G. Wurm
    • 2
  1. 1.Institut für Pharmakologie der Freien Universität BerlinBerlin 33Federal Republic of Germany
  2. 2.Institut für Pharmazie der Freien Universität BerlinBerlin 33Federal Republic of Germany

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