Skip to main content
SpringerLink
Log in

Anti-inflammatory activity of the flavonoid fraction of khat (Catha edulis Forsk)

  • New Anti-inflammatory Agents
  • Published:
Agents and Actions Aims and scope Submit manuscript

Abstract

The administration of the flavonid fraction, isolated from Khat (Catha edulis Forsk), in a dose of 200 mg/kg orally, produced a significant anti-inflammatory activity against the carrageenan induced paw oedema and cotton pellet granuloma in albino rats. The results were comparable with the standard anti-inflammatory drug oxyphenbutazone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. I. Khan andP. Kalix, Khat,plant with amphetamine like effects, TIPS5, 326–328 (1984).

    Google Scholar 

  2. M. Tariq, N.S. Parmar, A.M. Ageel, I.A. Al-Meshal,The gastric anti-ulcer activity of Khat (Catha edulis Forsk): Investigations on its flavonoid fraction. Res. Comm. Subst. Abuse5, 157–160 (1984).

    Google Scholar 

  3. A. Villar, M.A. Casco andM.J. Alcaraz,Anti-inflammatory and anti-ulcer properties of hypolaetin-8-glucoside, a novel plant flavonoid. J. Pharm., Pharmac.36, 820–823 (1984).

    Google Scholar 

  4. J.M. Harris andP.S.J. Spencer,A modified plethysmographic apparatus for recording volume changes in rat paw. J. Pharm. Pharmacol.14, 464 (1962).

    PubMed  Google Scholar 

  5. S. Goldstein, I. Shemano, R. Demes andJ.M. Beiler,Cotton pellet granuloma pouch method for evaluation of anti-inflammatory activity, Arch. Int. Pharmacodyn. Ther.165, 294–301 (1976).

    Google Scholar 

  6. N.S. Parmar andM.N. Ghosh,Current trend in flavonoid research. Ind. J. Pharmacol.12, 213–228 (1980).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. College of Pharmacy, King Saud University, P.O. Box 2457, 11451, Riyadh, Saudi Arabia

    I. A. Al-Meshal, M. Tariq, N. S. Parmar & A. M. Ageel

Authors
  1. I. A. Al-Meshal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Tariq
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. S. Parmar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. M. Ageel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Al-Meshal, I.A., Tariq, M., Parmar, N.S. et al. Anti-inflammatory activity of the flavonoid fraction of khat (Catha edulis Forsk). Agents and Actions 17, 379–380 (1986). https://doi.org/10.1007/BF01982654

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01982654

Keywords

Search

Navigation