Agents and Actions

, Volume 17, Issue 3–4, pp 342–346 | Cite as

Tissue culture methods for the investigation of anti-inflammatory drugs

  • K. Brune
  • R. Lanz
  • N. Müller
Experimental Models of Inflammation


Tissue culture methods are used increasingly in the investigation of anti-inflammatory drugs. Compared toin vivo experiments they offer the advantages of a) relative reproducibility, b) reduced cost, and c) simplified interpretation of results. Moreover, tissue culture methods can be applied without major ethical concern. The disadvantage of cell culture techniques is the need to re-checkin vivo the medical relevance of all data obtained. A few applications of cell culture methods are exemplified by results obtained in our laboratory from experiments using macrophages, endothelial cells and chondrocytes.


Endothelial Cell Cell Culture Tissue Culture Culture Method Culture Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • K. Brune
    • 1
  • R. Lanz
    • 1
  • N. Müller
    • 1
  1. 1.Department of Pharmacology and ToxicologyUniversity of Erlangen-NürnbergErlangenFRG

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