Summary
The absence of the methyl substituent at the 2′position of the cyclohexene ring of TCHP enhances the conversion rate as well as the yields of the 3′-hydroxy product obtained byStreptomyces natalensis and the 3′-keto product obtained byMycobacterium smegmatis.
Abbreviations
- TCHP:
-
1-(2″-thienyl)-3-(1′-cyclohexen-1′-yl)-1-propanone
- TCHP-OH:
-
1-(2″-thienyl)-3-(3′-hydroxyl-1′-cyclohexen-1′-yl)-1-propanone
- TCHP-ketone:
-
1-(2″-thienyl)-3-(1′-cyclohexen-1′-yl-3′-one)-1-propane
- TMCHP:
-
1-(2″-thienyl)-3-(2′-methyl-1′-cyclohexen-1′-yl)-propanone
References
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Plemenitaš, A., Belič, I. The effect of the methyl substituent on the bioconversion of cyclohexene derivatives. Appl Microbiol Biotechnol 24, 178–179 (1986). https://doi.org/10.1007/BF01982564
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DOI: https://doi.org/10.1007/BF01982564