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The effect of the methyl substituent on the bioconversion of cyclohexene derivatives

  • Applied Microbiology
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Summary

The absence of the methyl substituent at the 2′position of the cyclohexene ring of TCHP enhances the conversion rate as well as the yields of the 3′-hydroxy product obtained byStreptomyces natalensis and the 3′-keto product obtained byMycobacterium smegmatis.

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Abbreviations

TCHP:

1-(2″-thienyl)-3-(1′-cyclohexen-1′-yl)-1-propanone

TCHP-OH:

1-(2″-thienyl)-3-(3′-hydroxyl-1′-cyclohexen-1′-yl)-1-propanone

TCHP-ketone:

1-(2″-thienyl)-3-(1′-cyclohexen-1′-yl-3′-one)-1-propane

TMCHP:

1-(2″-thienyl)-3-(2′-methyl-1′-cyclohexen-1′-yl)-propanone

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Plemenitaš, A., Belič, I. The effect of the methyl substituent on the bioconversion of cyclohexene derivatives. Appl Microbiol Biotechnol 24, 178–179 (1986). https://doi.org/10.1007/BF01982564

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  • DOI: https://doi.org/10.1007/BF01982564

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