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, Volume 11, Issue 4, pp 417–420 | Cite as

Kybernetics of cardio-respiratory synchrony: Characterization by modulating cardiac frequency

  • K. E. Bucher
  • K. Bucher
Regulation of Respiration


The work concerns the special and particularly efficient kybernetic system which synchronizes respiratory and cardiac activities in rabbits. An experimental procedure is worked out to characterize its potentialities. It consists of an artificial, elective and continuous slowing down of cardiac frequency in left-side vagotomized animals. Whenever synchrony happens to exist — and this can be provided — such slowing down will tend to throw the two rhythms out of phase. The stronger the kybernetic system, then the more it should be able to outweigh such disturbing tendencies. The correlation between the speed of cardiac slowing and the number of synchronized breaths resisting such disturbances follows a hyperbolic course. Characteristics of this hyperbola offer a useful means of quantifying the kybernetic system.


Cardiac Activity Cardiac Frequency Cardiac Slowing Continuous Slowing Vagotomized Animal 
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  1. [1]
    K. Bucher,Ueber den Entstehungsmechanismus der pulssynchronen Atmung, Helv. physiol. pharmac. Acta2, 591–605 (1944).Google Scholar
  2. [2]
    K. Bucher,Das Herz als Schrittmacher für die Atmung, Natw. Med. Grdlg. forsch.1, 318–331 (1963).Google Scholar
  3. [3]
    K. Bucher andK.E. Bucher,Quantifying Drugs Influence on Cardiorespiratory Synchronism, Res. exp. Med.171, 25–31 (1977).Google Scholar
  4. [4]
    K. Bucher andK.E. Bucher,Cardio-respiratory Synchronisms: Synchrony with Artificial Circulation, Res. exp. Med.171, 33–39 (1977).Google Scholar
  5. [5]
    K. Bucher, H. Schwitter, B. Hool-Zulauf andE. Batschelet,Links Between Cardiac and Respiratory Rhythmicity, Res. exp. Med.157, 281–288 (1972).Google Scholar
  6. [6]
    P. Engel, A. Jaeger andG. Hildebrandt,Ueber die Beeinflussung der Frequenz- und Phasenkoordination zwischen Herzschlag und Atmung durch verschiedene Narkotica, Arzneimittel-Forsch.22, 1460–1468 (1972).Google Scholar
  7. [7]
    D.H. Garrow,Linking of Cardiac and Respiratory Rhythms in New-born Babies, J. Physiol.203, 86–87 (1969).Google Scholar
  8. [8]
    G. Hildebrandt,Die Koordination rhythmischer Funktionen beim Menschen, 73. Kongr. f. inn. Med. 921–941 (1967b).Google Scholar
  9. [9]
    P. Hinderling andK. Bucher,Synchronismen zwischen Kreislauf und Atmung am Menschen, Helv. physiol. pharmac. Acta23, 374–381 (1965).Google Scholar

Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • K. E. Bucher
    • 1
  • K. Bucher
    • 1
  1. 1.Department of Pharmacology (701)Biocenter of the University of BasleBasleSwitzerland

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