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Experientia

, Volume 34, Issue 10, pp 1323–1325 | Cite as

Species-dependent stereospecific serum protein binding of the oral anticoagulant drug phenprocoumon

  • W. Schmidt
  • E. Jähnchen
Specialia

Summary

13 mammalian species are classified into 3 clearcut groups with respect to the stereospecific serum proteinbinding of phenprocoumon: 2 groups showing opposed stereospecific binding characteristics and a 3rd group exhibiting no stereospecific binding. Structural differences in the albumin molecule account for these stereospecific differences in serum protein-binding.

Keywords

Albumin Serum Protein Structural Difference Mammalian Species Binding Characteristic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • W. Schmidt
    • 1
  • E. Jähnchen
    • 1
  1. 1.Department of PharmacologyUniversity of MainzMainz(Federal Republic of Germany)

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