European Journal of Clinical Microbiology

, Volume 3, Issue 4, pp 282–284 | Cite as

Interferons and viral infections

  • P. G. Higgins


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  1. 1.
    Baron, S., Dianzani, F.: General consideration of the interferon system. Texas Reports on Biology and Medicine 1977, 35: 1–10.Google Scholar
  2. 2.
    Isaacs, D., Clarke, J. R., Tyrrell, D. A. J., Webster, A. D. B., Valman, H. B.: Deficient production of leucocyte interferon (interferon-α) in vitro and in vivo in children with recurrent respiratory tract infection. Lancet 1981, ii: 950–952.Google Scholar
  3. 3.
    Levin, S., Hahn, T.: Interferon system in acute virus hepatitis. Lancet 1982, i: 592–594.Google Scholar
  4. 4.
    Scott, G. M., Cartwright, T., LeDu, G., Dicker, D.: Effect of human fibroblast interferon on vaccination in volunteers. Journal of Biological Standardization 1978, 6: 73–76.Google Scholar
  5. 5.
    Merigan, T. C., Reed, S. E., Hall, T. S., Tyrrell, D. A. J.: Inhibition of respiratory virus infection by locally applied interferon. Lancet 1973, i: 563–567.Google Scholar
  6. 6.
    Scott, G. M., Phillpotts, R. J., Wallace, J., Secher, D. S., Cantell, K., Tyrrell, D. A. J.: Purified interferon as protection against rhinovirus infection. British Medical Journal 1982, i: 1822–1825.Google Scholar
  7. 7.
    Samo, T. C., Greenberg, S. B., Couch, R. B., Quarles, J., Johnson, P. E., Hook, S., Harmon, M. W.: Efficacy and tolerance of intranasally applied recombinant leucocyte A interferon in normal volunteers. Journal of Infectious Diseases 1983, 148: 535–542.Google Scholar
  8. 8.
    Hayden, F. G., Gwaltney, J. M.: Intranasal interferonα 2 for prevention of rhinovirus infection and illness. Journal of Infectious Diseases 1983, 148: 543–550.Google Scholar
  9. 9.
    Higgins, P. G., Phillpotts, R. J., Scott, G. M., Wallace, J., Bernhardt, L. L., Tyrrell, D. A. J.: Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers. Antimicrobial Agents and Chemotherapy 1983, 24: 713–715.Google Scholar
  10. 10.
    Pazin, G. J., Armstrong, J. A., Lam, M. T., Tarr, G. C., Jannetta, P. J., Ho, M.: Prevention of reactivated herpes simplex infection by human leukocyte interferon after operation on the trigeminal root. New England Journal of Medicine 1979, 301: 225–230.Google Scholar
  11. 11.
    Cheeseman, S. H., Rubin, R. H., Stewart, J. A., Tolkoff-Rubin, N. E., Cosimi, A. B., Cantell, K., Gilbert, J., Winkle, S., Herrin, J. T., Black, P. H., Russell, P. S., Hirsch, M. S.: Controlled clinical trial of prophylactic human-leukocyte interferon in renal transplantation. Effects on cytomegalovirus and herpes simplex virus infections. New England Journal of Medicine 1979, 300: 1345–1349.Google Scholar
  12. 12.
    Hirsch, M. S., Schooley, R. T., Cosimi, A. B., Russell, P. S., Delmonico, F. L., Tolkoff-Rubin, N. E., Herrin, J. T., Cantell, K., Farrell, M. L., Rota, T. R., Rubin, R. H.: Effects of interferon-alpha on cytomegalovirus reactivation syndromes in renal transplant recipients. New England Journal of Medicine 1983, 308: 1489–1493.Google Scholar
  13. 13.
    Jones, B. R., Coster, D. J., Faloon, M. G., Cantell, K.: Topical therapy of ulcerative herpectic keratitis with human interferon. Lancet 1976, ii: 128.Google Scholar
  14. 14.
    Sundmacher, R., Neumann-Haefelin, D., Cantell, K.: Successful treatment of dendritic keratitis with human leucocyte interferon — a controlled clinical study. Graefes Archiv für Klinische und Experimentelle Opthalmologie 1976, 201: 39–45.Google Scholar
  15. 15.
    Sundmacher, R., Cantell, K., Neumann-Haefelin, D.: Combination therapy of dendritic keratitis with trifluorothymidine and interferon. Lancet 1978, ii: 687.Google Scholar
  16. 16.
    Merigan, T. C., Rand, K. H., Pollard, R. B., Abdallah, P. S., Jordan, G. W., Fried, R. P.: Human leukocyte interferon for the treatment of herpes zoster in patients with cancer. New England Journal of Medicine 1978, 298: 981–987.Google Scholar
  17. 17.
    Arvin, A. M., Kushner, J. H., Feldman, S., Baehner, R. L., Hammond, D., Merigan, T. C.: Human leukocyte interferon for the treatment of varicella in children with cancer. New England Journal of Medicine 1982, 306: 761–765.Google Scholar
  18. 18.
    Greenberg, H. B., Pollard, R. B., Lutwick, L. I., Gregory, P. B., Robinson, W. S., Merigan, T. C.: Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. New England Journal of Medicine 1976, 295: 517–522.Google Scholar
  19. 19.
    Scullard, G. H., Pollard, R. B., Smith, J. L., Sacks, S. L., Gregory, P. B., Robinson, W. S., Merigan, T. C.: Anti-viral treatment of chronic hepatitis B virus infection. 1. Changes in viral markers with interferon combined with adenine arabinoside. Journal of Infectious Diseases 1981, 143: 772–783.Google Scholar
  20. 20.
    Arvin, A. M., Schmidt, N. J., Cantell, K., Merigan, T. C.: Alpha interferon administration to infants with congential rubella. Antimicrobial Agents and Chemotherapy 1982, 21: 259–261.Google Scholar
  21. 21.
    Emödi, G., O'Reilly, R., Müller, A., Everson, L. K., Binswanger, U., Just, M.: Effect of human exogenous leukocyte interferon in cytomegalovirus infections. Journal of Infectious Diseases 1976, 133: A199–204.Google Scholar
  22. 22.
    Arvin, A. M., Yeager, A. S., Merigan, T. C.: Effect of leukocyte interferon on urinary excretion of cytomegalovirus by infants. Journal of Infectious Diseases 1976, 133: A205–210.Google Scholar
  23. 23.
    Ikić, D., Bosnić, N., Smerdel, S., Jušić, D., Šooš, E., Delimar, N.: Double blind clinical study with human leukocyte interferon in the therapy of condylomata acuminata. In: D. Ikić (ed.): Proceedings of a Symposium on Clinical Use of Interferon. Yugoslav Academy of Sciences and Arts, Zagreb, 1975, p. 229–233.Google Scholar
  24. 24.
    Scott, G. M., Csonka, G. W.: Effect of injections of small doses of human fibroblast interferon into genital warts: a pilot study. British Journal of Venereal Disease 1979, 55: 442–445.Google Scholar
  25. 25.
    Haglund, S., Lundquist, P. G., Cantell, K., Strander, H.: Interferon therapy in juvenile laryngeal papillomatosis. Archives of Otolaryngology 1981, 107: 327–332.Google Scholar
  26. 26.
    Phillpotts, R. J., Scott, G. M., Higgins, P. G., Wallace, J., Tyrrell, D. A. J., Gauci, C. L.: An effective dosage regimen for prophylaxis against rhinovirus infection by intranasal administration of HuIFN-α 2. Antiviral Research 1983, 3: 121–136.Google Scholar
  27. 27.
    Merigan, T. C., Gallagher, J. G., Pollard, R. B., Arvin, A. M.: Short-course human leukocyte interferon in treatment of herpes zoster in patients with cancer. Antimicrobial Agents and Chemotherapy 1981, 19: 193–195.Google Scholar

Copyright information

© Vieweg Publishing 1984

Authors and Affiliations

  • P. G. Higgins
    • 1
  1. 1.MRC Common Cold UnitSalisburyEngland

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