Experientia

, Volume 36, Issue 10, pp 1180–1181 | Cite as

Evidence for an involvement of acetylcholine in self-stimulation of the prefrontal cortex in the rat

  • F. Mora
  • F. Vives
  • F. Alba
Specialia

Summary

The effects of injections of antagonists of muscarinic and nicotinic receptors on self-stimulation of the prefrontal cortex in the rat were studied. The results of this investigation suggest that acetylcholine is involved in self-stimulation of the prefrontal cortex through activation of muscarinic receptors, and also suggest a possible interaction between acetylcholine and dopamine in mediating self-stimulation of this area of the brain.

Keywords

Dopamine Acetylcholine Prefrontal Cortex Muscarinic Receptor Nicotinic Receptor 

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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • F. Mora
    • 1
  • F. Vives
    • 1
  • F. Alba
    • 1
  1. 1.Department of Physiology, School of MedicineUniversity of GranadaGranada(Spain)

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