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Experientia

, Volume 36, Issue 10, pp 1153–1154 | Cite as

Inhibition of thiamine transport in baker's yeast by methylene blue

  • A. Iwashima
  • H. Nishimura
  • H. Nishino
Specialia

Summary

Methylene blue was found to inhibit thiamine transport competitively (Ki=0.63 μM) in baker's yeast. The dye was also effective in abolishing the growth inhibition ofSaccharomyces cerevisiae by pyrithiamine which is known to be taken up by a common transport system for thiamine in yeast cells. A possible mechanism for the inhibition by methylene blue of the thiamine transport system in baker's yeast is discussed.

Keywords

Methylene Growth Inhibition Methylene Blue Yeast Cell Transport System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • A. Iwashima
    • 1
  • H. Nishimura
    • 1
  • H. Nishino
    • 1
  1. 1.Department of BiochemistryKyoto Prefectural University of MedicineKyoto(Japan)

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