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Effects of 1.25 dihydroxyvitamin D3 on calcium uptake, into rat intestine after chronic oral cadmium administration

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Summary

Calcium influx into rat intestine was investigated, in vitro, after cadmium chronic oral exposure. In active calcium transport, pretreatment by 1.25 dihydroxyvitamin D3 prevents the effect of cadmium on the maximal influx value Jm and leads to an increase of the half-saturation constant Kt.

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Authors and Affiliations

  1. Laboratoire de Physique, Faculté des Sciences Pharmaceutiques, 31, allées Jules Guesde, F-31077, Toulouse cedex, France

    M. J. Fauran-Clavel, J. Oustrin & F. Fauran

Authors
  1. M. J. Fauran-Clavel
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  2. J. Oustrin
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  3. F. Fauran
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Additional information

Acknowledgments. The authors wish to express their grateful thanks to F. Hoffmann-La Roche Co. in Basle, Switzerland, who provided them with chemically synthesized vitamin D3 metabolite.

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Fauran-Clavel, M.J., Oustrin, J. & Fauran, F. Effects of 1.25 dihydroxyvitamin D3 on calcium uptake, into rat intestine after chronic oral cadmium administration. Experientia 36, 1147–1149 (1980). https://doi.org/10.1007/BF01976091

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