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Comparison of the time courses of luteinizing hormone (LH) secretion rates during continuous stimulation by LH-releasing hormone (LH-RH) in vivo and in vitro

Experientia volume 42, pages 60–62 (1986)Cite this article

Summary

The patterns of LH secretion during constant stimulation of the pituitary glands of estradiol-treated ovariectomized rats with a maximally stimulating amount of LH-RH in vivo and in vitro correspond with each other qualitatively and quantitatively. In vitro the changes with time of the LH secretion rate are somewhat retarded, especially the occurrence of desensitization.

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Affiliations

  1. Department of Pharmacology of the University of Leiden, P.O. Box 9503, 2300 RA, Leiden, (The Netherlands)

    J. de Koning, A. M. I. Tijssen, J. A. M. J. van Dieten & G. P. van Rees

  2. Department of Obstetrics and Gynecology, Academic Hospital, Oostersingel 59, 9713 EZ, Groningen, (The Netherlands)

    T. R. Koiter & G. A. Schuiling

Authors
  1. J. de Koning
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  2. A. M. I. Tijssen
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  3. J. A. M. J. van Dieten
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  4. T. R. Koiter
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  5. G. A. Schuiling
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  6. G. P. van Rees
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de Koning, J., Tijssen, A.M.I., van Dieten, J.A.M.J. et al. Comparison of the time courses of luteinizing hormone (LH) secretion rates during continuous stimulation by LH-releasing hormone (LH-RH) in vivo and in vitro. Experientia 42, 60–62 (1986). https://doi.org/10.1007/BF01975896

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  • DOI: https://doi.org/10.1007/BF01975896

Key words

  • Pituitary gland
  • luteinizing hormone (LH)
  • luteinizing hormone-releasing hormone (LH-RH)
  • LH-RH releasing activity in vivo vs in vitro