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Value of new quinolones in the treatment and prophylaxis of infectious diseases: Introductory remarks

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References

  1. Neu, H. C. Clinical uses of the quinolones. Lancet 1987, ii: 1319–1322.

    Article  Google Scholar 

  2. Paton, J. H., Reeves, D. S. Fluoroquinolone antibiotics. Microbiology, pharmacokinetics and clinical use. Drugs 1988, 36: 193–228.

    PubMed  Google Scholar 

  3. Rubinstein, E., Adams, D., Moellering, R., Waldvogel, F. (ed.): International symposium on new quinolones. Reviews of Infectious Diseases 1988, 10, Supplement 1: 1–271.

  4. Wolfson, J. S., Hooper, D. C. (ed.): Quinolone antimicrobial agents. American Society for Microbiology, Washington, DC, 1989.

    Google Scholar 

  5. Wolfson, J. S., Hooper, D. C., Swartz, M. N. Mechanisms of action of and resistance to quinolone antimicrobial agents. In: Wolfson, J. S., Hooper, D. C. (ed.): Quinolone antimicrobial agents. American Society for Microbiology, Washington, DC, 1989, p. 5–34.

    Google Scholar 

  6. Domagala, J. M., Hanna, L. D., Heifetz, C. L., Hutt, M. P., Mich, T. F., Sanchez, J. P., Solomon, M. New structure-activity relationships of quinolone anti-bacterials using the target enzyme. The development and application of a DNA gyrase assay. Journal of Medicinal Chemistry 1986, 29: 394–404.

    Article  PubMed  Google Scholar 

  7. Mitscher, L. A., Sharma, P. N., Chu, D. T. W., Shen, L. L., Pernet, A. G. Chiral DNA gyrase inhibitors. I. Synthesis and antimicrobial activity of the enantiomers of 6-fluoro-7-(1-piperazinyl)-1-12′-trans-phenyl-1′-cyclopropyl)-1,4-dihydro-4-oxoquinolone-3-carboxylic acid. Journal of Medicinal Chemistry 1986, 29: 2044–2047.

    Article  PubMed  Google Scholar 

  8. Crumplin, G. C. Aspects of chemistry in the development of the 4-quinolone antibacterial agents. Reviews of Infectious Diseases 1988, 10, Supplement 1: 2–9.

    Google Scholar 

  9. Hooper, D. C., Wolfson, J. S. Mode of action of the quinolone antimicrobial agents. Reviews of Infectious Diseases 1988, 10, Supplement 1: 14–21.

    Google Scholar 

  10. Chu, D. T. W., Fernandes, P. B. Structure-activity relationships of the fluoroquinolones. Antimicrobial Agents and Chemotherapy 1989, 33: 131–135.

    PubMed  Google Scholar 

  11. Fernandes, P. B., Chu, D. T. W., Swanson, R. N., Ramer, N. R., Hanson, C. W., Bower, R. R., Stamm, J. M., Hardy, D. J. A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria. Antimicrobial Agents and Chemotherapy 1988, 32: 27–32.

    PubMed  Google Scholar 

  12. Espinoza, A. M., Chin, N.-C., Novelli, A., Neu, H. C. Comparative in vitro activity of a new fluorinated 4-quinolone T-3262 (A-60969). Antimicrobial Agents and Chemotherapy 1988, 32: 663–670.

    PubMed  Google Scholar 

  13. Fujimaki, K., Noumi, T., Saikawa, I., Inoue, M., Mitsuhashi, S. In vitro and in vivo antibacterial activities of T-3262, a new fluoroquinolone. Antimicrobial Agents and Chemotherapy 1988, 32: 827–833.

    PubMed  Google Scholar 

  14. Wise, R., Ashby, J. P., Andrews, J. M. In vitro activity of PD 127,391, an enhanced-spectrum quinolone. Antimicrobial Agents and Chemotherapy 1988, 32: 1251–1256.

    PubMed  Google Scholar 

  15. Norrby, S. R., Jonsson, M. Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative. Antimicrobial Agents and Chemotherapy 1988, 32: 1278–1281.

    PubMed  Google Scholar 

  16. Montay, G., Goueffon, Y., Roquet, F. Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans. Antimicrobial Agents and Chemotherapy 1984, 25: 463–472.

    PubMed  Google Scholar 

  17. Granneman, G. R., Snyder, K. M., Shu, V. S. Difloxacin metabolism and pharmacokinetics in humans after single oral doses. Antimicrobial Agents and Chemotherapy 1986, 30: 689–693.

    PubMed  Google Scholar 

  18. Wise, R., Kirkpatrick, B., Ashby, J., Griggs, D. J. Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone. Antimicrobial Agents and Chemotherapy 1987, 31: 161–163.

    PubMed  Google Scholar 

  19. Cozzarelli, N. R. DNA gyrase and the supercoiling of DNA. Science 1980, 207: 953–960.

    PubMed  Google Scholar 

  20. Gellert, M. DNA topoisomerases. Annual Review of Biochemistry 1981, 50: 879–910.

    Article  PubMed  Google Scholar 

  21. Wang, J. C. DNA topoisomerases. Annual Review of Biochemistry 1985, 54: 655–697.

    Article  Google Scholar 

  22. Gellert, M., Mizuuchi, K., O'Dea, M. H., Nash, H. A. DNA gyrase: an enzyme that introduces superhelical turns into DNA. Proceedings of the National Academy of Sciences USA 1976, 73: 3872–3876.

    Google Scholar 

  23. Sugino, A., Peebles, C. L., Kreuzer, K. N., Cozzarelli, N. R. Mechanism of action of nalidixic acid: purification ofEscherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proceedings of the National Academy of Sciences USA 1977, 74: 4767–4771.

    Google Scholar 

  24. Gellert, M., Mizuuchi, K., O'Dea, M. H., Itoh, T., Tomizawa, J. Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. Proceedings of the National Academy of Sciences USA 1977, 74: 4772–4776.

    Google Scholar 

  25. Shen, L. L., Pernet, A. G. Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA. Proceedings of the National Academy of Sciences USA 1985, 82: 307–311.

    Google Scholar 

  26. Shen, L. L., Kohlbrenner, W. E., Weigl, D., Baranowski, J. Mechanism of quinolone inhibition of DNA gyrase. Journal of Biological Chemistry 1989, 264: 2973–2978.

    PubMed  Google Scholar 

  27. Mitsuhashi, S. Comparative antibacterial activity of new quinolone-carboxyclic acid derivatives. Reviews of Infectious Diseases 1988, 10, Supplement 1: 27–31.

    Google Scholar 

  28. Eliopoulos, G. M., Eliopoulos, C. T. Quinolone antimicrobial agents: activity in vitro. In: Wolfson, J. S., Hooper, D. C. (ed.): Quinolone antimicrobial agents. American Society for Microbiology, Washington, DC, 1989, p. 35–70.

    Google Scholar 

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Wolfson, J.S., Murray, B.E. Value of new quinolones in the treatment and prophylaxis of infectious diseases: Introductory remarks. Eur. J. Clin. Microbiol. Infect. Dis. 8, 1071–1074 (1989). https://doi.org/10.1007/BF01975173

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