, Volume 36, Issue 4, pp 402–403 | Cite as

Gene activity int eh carnation-light synthetic lethal inDrosophila melanogaster

  • H. Nickla
  • T. Lilly
  • A. McCarthy


A gynandromorphic study of the carnation-light synthetic lethal revealed a site of lethal interaction (focus) in nerve tissue. Because both the carnation and light loci are known to be active in non-nervous tissue we have interpreted our results in terms of a model which accounts for diminution of developmental potential as a result of irreversible gene repression rather than selective gene activation.


Nerve Tissue Malpighian Tube Pteridine Male Tissue Light Locus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 2.
    Y. Hotta and S. Benzer, Nature240, 527 (1972).CrossRefPubMedGoogle Scholar
  2. 3.
    P. Bryant and M. Zornetzer, Genetics75, 623 (1973).PubMedPubMedCentralGoogle Scholar
  3. 4.
    P. Ripoll and A. Garcia-Bellido, Nature241, 15 (1973).Google Scholar
  4. 5.
    A. Shearn, Am. Zool.17, 585 (1977).CrossRefGoogle Scholar
  5. 6.
    G. Malacinski, Am. Zool.18, 195 (1978).CrossRefGoogle Scholar
  6. 7.
    A. Sturtevant, Z. wiss. Zool.135, 323 (1929).Google Scholar
  7. 8.
    T. Wright, Adv. Genet.15, 261 (1970).PubMedGoogle Scholar
  8. 9.
    A. Garcia-Bellido and P. Santa Maria, Genetics88, 469 (1978).PubMedPubMedCentralGoogle Scholar
  9. 10.
    H. Nickla, Nature268, 638 (1977).CrossRefPubMedGoogle Scholar
  10. 11.
    G. Beadle and B. Ephrussi, Genetics21, 225 (1936).PubMedPubMedCentralGoogle Scholar
  11. 12.
    R. Brown, thesis, Creighton University 1973.Google Scholar
  12. 13.
    J. Flanagan, Genetics85, 587 (1977).PubMedPubMedCentralGoogle Scholar
  13. 14.
    L. Pasztor, Genetics68, 245 (1971).PubMedPubMedCentralGoogle Scholar
  14. 15.
    D. Lindsley and E. Grell, Carnegie Inst. Wash. Publ.1968, 627.Google Scholar
  15. 16.
    J. Hall, W. Gelbart and D. Kankel, in: The Genetics and Biology ofDrosophila, p. 265. Ed. M. Ashburner and E. Novitski, Academic Press, New York 1976.Google Scholar
  16. 17.
    D. Paulson, in: Biology ofDrosophila, p. 168. Ed. M. Demerec. Hafner, New York 1965.Google Scholar
  17. 18.
    A. Caplan and C. Ordahl, Science201, 120 (1978).CrossRefPubMedGoogle Scholar
  18. 19.
    H. Nickla, Can. J. Genet. Cytol.14, 391 (1972).CrossRefPubMedGoogle Scholar
  19. 20.
    G. Beadle, Am. Nat.71, 277 (1937).CrossRefGoogle Scholar

Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • H. Nickla
    • 1
  • T. Lilly
    • 1
  • A. McCarthy
    • 1
  1. 1.Department of BiologyCreighton UniversityOmahaUSA

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