, Volume 36, Issue 4, pp 385–386 | Cite as

Active transport of dimethialium inSaccharomyces cerevisiae

  • A. Iwashima
  • H. Nishimura
  • K. Sempuku


Dimethialium, a derivative of thiamine which has a methyl group in place of hydroxyethyl group at the 5-position of the thiazole moiety, was found to be accumulated in nonproliferating cells ofSaccharomyces cerevisiae by the same transport mechanism for thiamine. The results strongly support the supposition that thiamine as well as dimethialium can be transported and accumulated without obligatory phosphorylation in yeast cells, since dimethialium is not phosphorylated by yeast thiamine pyrophosphokinase.


Thiamine Mango Fruit Hydroxyethyl Group Thiochrome Thiamine Transport 
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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • A. Iwashima
    • 1
  • H. Nishimura
    • 1
  • K. Sempuku
    • 1
  1. 1.Department of BiochemistryKyoto Prefectural University of MedicineKyotoJapan

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