Summary
Several analogs of precocene have been synthesized and evaluated as potential inhibitors of juvenile hormone onLocusta migratoria. Only 5,7-dimethoxy-2,2-dimethylchromene was active; its ED50 and LD50 were measured and compared to those of precocene I and II.
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Acknowledgments. This work was supported by grants from the Natural Sciences and Engineering Research Council of Canada and the ‘Ministère de l'Education du Québec’. We are grateful to Gaston Grégoire for rearing the insects.
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Chênevert, R., Perron, J.M., Paquin, R. et al. Activity of precocene analogs onLocusta migratoria migratorioides (R. and F.). Experientia 36, 379–380 (1980). https://doi.org/10.1007/BF01975097
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DOI: https://doi.org/10.1007/BF01975097