, Volume 36, Issue 4, pp 377–379 | Cite as

Structure and toxicity of the alkaloids of Russian comfrey (Symphytum x uplandicum Nyman), a medicinal herb and item of human diet

  • C. C. J. Culvenor
  • M. Clarke
  • J. A. Edgar
  • J. L. Frahn
  • M. V. Jago
  • J. E. Peterson
  • L. W. Smith


Eight pyrrolizidine alkaloids of hepatotoxic type have been indentified in leaves ofSymphytum × uplandicum The combined alkaloids exhibit chronic hepatotoxicity in rats.


Alkaloid Juvenile Hormone Pyrrolizidine Alkaloid Anhydrous Potassium Carbonate Total Plasma Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • C. C. J. Culvenor
    • 1
  • M. Clarke
    • 1
  • J. A. Edgar
    • 1
  • J. L. Frahn
    • 1
  • M. V. Jago
    • 1
  • J. E. Peterson
    • 1
  • L. W. Smith
    • 1
  1. 1.CSIRO, Division of Animal HealthParkvilleAustralia

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