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Hyperintense lesions of the globus pallidus on MRI in children with chronic liver disease

  • Gastroenterology/Hepatology
  • Original Paper
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

In three children with chronic liver disease of different aetiology without obvious hepatic encephalopathy, bilateral and symmetrical hyperintensity of the globus pallidus in T1-weighted images was found on cranial MRI. Reversibility was shown in one child with auto-immune hepatitis after normalisation of liver function tests under immuno-suppressive therapy.

As central nervous system involvement in liver disease is only partially understood, brain imaging by MRI offers a potential additional tool to further elucidate the incidence and time course of previously undetected brain alterations.

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Abbreviations

CNS :

central nervous system

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Authors and Affiliations

  1. Department of Paediatrics, University Hospital, Moorenstrasse 5, D-40225, Düsseldorf, Germany

    Antje Ballauff & Thomas Voit

  2. Department of Radiology, University of Düsseldorf, Germany

    Volker Engelbrecht

Authors
  1. Antje Ballauff
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  2. Volker Engelbrecht
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  3. Thomas Voit
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Ballauff, A., Engelbrecht, V. & Voit, T. Hyperintense lesions of the globus pallidus on MRI in children with chronic liver disease. Eur J Pediatr 153, 802–806 (1994). https://doi.org/10.1007/BF01972887

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  • DOI: https://doi.org/10.1007/BF01972887

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