Skip to main content

Advertisement

SpringerLink
Log in

DisseminatedScedosporium inflatum infection in a patient with acute myeloblastic leukemia

  • Notes
  • Published:
European Journal of Clinical Microbiology and Infectious Diseases Aims and scope Submit manuscript

Abstract

A case of disseminatedScedosporium inflatum infection occurring in a neutropenic patient with acute myeloblastic leukemia is reported.Scedosporium inflatum was isolated from skin lesions, blood, urine and vitreous cultures. Amphotericin B treatment was ineffective in avoiding hematogenous spread. At autopsy, hyphae and ovoid conidia with truncate bases consistent with the morphology ofScedosporium inflatum were found in the lungs, kidneys, myocardium, liver, thyroid, spleen, lymph nodes, brain and the left eye. This is the first report of disseminatedScedosporium inflatum infection and the first time this organism has been isolated from a patient in Europe.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Malloch D, Salkin IF A new species ofScedosporium associated with osteomyelitis in humans. Mycotaxon 1984, 21: 247–255.

    Google Scholar 

  2. Salkin IF, McGinnis MR, Dykstra MJ, Rinaldi MG Scedosporium inflatum, an emerging pathogen. Journal of Clinical Microbiology 1988, 26: 498–503.

    PubMed  Google Scholar 

  3. Wilson CM, O'Rourke EJ, McGinnis MR, Salkin IF Scedosporium inflatum: clinical spectrum of a newly recognized pathogen. Journal of Infectious Diseases 1990, 161: 102–107.

    PubMed  Google Scholar 

  4. Malekzadeh M, Overturf GD, Auerbach SB, Wong L, Hirsch M Chronic, recurrent osteomyelitis caused byScedosporium inflatum. Pediatric Infectious Disease Journal 1990, 9: 357–359.

    PubMed  Google Scholar 

  5. Dykstra MJ, Salkin IF, McGinnis MR An ultrastructural comparison of conidiogenesis inScedosporium apiospermum, Scedosporium inflatum andScopulariopsis brumptii. Mycologia 1989, 81: 896–904.

    Google Scholar 

  6. Travis LB, Roberts GD, Wilson WR Clinical significance ofPseudallescheria boydii: a review of 10 years' experience. Mayo Clinic Proceedings 1985, 60: 531–537.

    PubMed  Google Scholar 

  7. Rippon JW Pseudallescheriasis. In: Rippon JW (ed): Medical mycology. Saunders, Philadelphia, PA, 1988, p. 651–680.

    Google Scholar 

  8. Guyotat D, Piens MA, Bouvier R, Fiere D A case of disseminatedScedosporium apiospermum infection after bone marrow transplantation. Mykosen 1987, 30: 151–154.

    PubMed  Google Scholar 

  9. Smith AG, Crain SM, DeJongh C, Thomas GM, Vigorito RD Systemic pseudallescheriasis in a patient with acute myelocytic leukemia. Mycopathologia 1985, 90: 85–89.

    Article  PubMed  Google Scholar 

  10. Anaissie EJ, Bodey GP, Rinaldi MG Emerging fungal pathogens. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 323–330.

    Google Scholar 

  11. Clarck SC The human hematopoietic colony-stimulating factors. Science 1987, 236: 1229–1237.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, La Fe University Hospital, 46009, Valencia, Spain

    J. Marin, M. A. Sanz & J. L. Menezo

  2. Department of Hematology, La Fe University Hospital, 46009, Valencia, Spain

    G. F. Sanz

  3. Department of Microbiology, La Fe University Hospital, 46009, Valencia, Spain

    M. L. Martínez

  4. Department of Pathology, La Fe University Hospital, 46009, Valencia, Spain

    M. Prieto

  5. Biology and Microbiology Unit, School of Medicine, Barcelona University, 43201, Reus, Tarragona, Spain

    J. Guarro

  6. Mycology Unit, Institut Pasteur, 75015, Paris, France

    E. Gueho

Authors
  1. J. Marin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. A. Sanz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. F. Sanz
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. Guarro
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. L. Martínez
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. M. Prieto
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. E. Gueho
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. J. L. Menezo
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marin, J., Sanz, M.A., Sanz, G.F. et al. DisseminatedScedosporium inflatum infection in a patient with acute myeloblastic leukemia. Eur. J. Clin. Microbiol. Infect. Dis. 10, 759–761 (1991). https://doi.org/10.1007/BF01972505

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01972505

Keywords

Search

Navigation