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Antibody response against autologous and heterologous isolates ofBorrelia burgdorferi in four patients with Lyme neuroborreliosis

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Abstract

Serum and cerebrospinal fluid (CSF) samples from four patients with Lyme neuroborreliosis were analyzed for IgM and IgG antibodies by an indirect enzyme immunoassay with the four patients' own CSF isolate ofBorrelia burgdorferi and two tick isolates, strains STG152 and B31, as antigens. No major differences in the antibody response were found comparing autologous and heterologous strains as sonicate antigens, although a tendency towards a stronger response to the autologous isolates was noted in samples from two patients.

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  1. Department of Infectious Diseases and Department of Clinical Bacteriology, Danderyd Hospital, 182 88, Danderyd, Sweden

    M. Karlsson

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  1. M. Karlsson
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Karlsson, M. Antibody response against autologous and heterologous isolates ofBorrelia burgdorferi in four patients with Lyme neuroborreliosis. Eur. J. Clin. Microbiol. Infect. Dis. 10, 742–745 (1991). https://doi.org/10.1007/BF01972499

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