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Antifertilityeffects of clonidine in laying hens

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Summary

Clonidine was anovulatory and markedly antigonadal in laying hens when infused for 1 week from minipump implants at daily rates of 1.08 mg per hen or greater. The ovaries of hens treated with clonidine responded to FSH injections which suggests that the antigonadal effect of clonidine resulted from a reduction in the output of gonadotropin by the pituitary. These data suggest that α2 receptors may be important in regulating avian fertility.

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Authors and Affiliations

  1. Department of Poultry Parasitology and Nutrition, Merck Sharp and Dohme Research Laboratories, P.O. Box 2000, 07065, Rahway, N.J., USA

    R. M. Weppelman, R. L. Tolman, A. Ann Van Iderstine, L. Peterson & G. Olson

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  1. R. M. Weppelman
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  2. R. L. Tolman
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  3. A. Ann Van Iderstine
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  4. L. Peterson
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  5. G. Olson
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Weppelman, R.M., Tolman, R.L., Ann Van Iderstine, A. et al. Antifertilityeffects of clonidine in laying hens. Experientia 37, 995–997 (1981). https://doi.org/10.1007/BF01971800

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  • DOI: https://doi.org/10.1007/BF01971800

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