Summary
Centrifugation into a rapid cell fixative is used to determine the conformation of red cells at various pH-values as a measure of red cell deformability. Discocytes show a good deformation into handbag-like forms; echinocytes and stomatocytes have reduced deformability with characteristic shapes of deformation.
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Nagasawa, T. Deformation of transforming red cells in various pH solutions. Experientia 37, 977–978 (1981). https://doi.org/10.1007/BF01971789
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DOI: https://doi.org/10.1007/BF01971789