Skip to main content
Log in

Presence of double stranded regions of viral RNA in infected cells

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Ribonuclease treatment of rhinovirus-infected human embryo lung cells after cell disruption reveals that double stranded RNA is present in the preparation before nucleic acids are extracted with phenol. This shows that the hydrogen bonding between complementary molecules of viral RNA which occurs in infected cells is not a result of the extraction of RNA with phenol.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. S. Spiegelman, N. R. Pace, D. R. Mills, R. Levisohn, T. S. Eikhom, M. M. Taylor, R. L. Peterson and D. H. L. Bishop, Cold Spring Harb. Symp. quant. Biol.33, 101 (1968).

    Article  CAS  PubMed  Google Scholar 

  2. C. Weissmann, G. Feix and H. Slor, Cold Spring Harb. Symp. quant. Biol.33, 83 (1968).

    Article  CAS  PubMed  Google Scholar 

  3. D. Baltimore, Science192, 632 (1976).

    Article  CAS  PubMed  Google Scholar 

  4. T. U. Keil and P. H. Hofschneider, Biochim. biophys. Acta312, 297 (1973).

    Article  CAS  PubMed  Google Scholar 

  5. S. S. Thach and R. E. Thach, J. molec. Biol.81, 367 (1973).

    Article  CAS  PubMed  Google Scholar 

  6. A. Zilberstein, P. Federman, L. Shulman and M. Revel, FEBS Lett.68, 119 (1976).

    Article  CAS  PubMed  Google Scholar 

  7. J. Cooper and P. J. Farrell, Biochem. biophys. Res. Commun.77, 124 (1977).

    Article  CAS  PubMed  Google Scholar 

  8. A. Zilberstein, A. Kimchi, A. Schmidt and M. Revel, Proc. natl Acad. Sci. USA75, 4734 (1978).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. I. M. Kerr and R. E. Brown, Proc. natl Acad. Sci. USA75, 256 (1978).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. L. A. Ball and C. N. White, Proc. natl Acad. Sci. USA75, 1167 (1978).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. A. Schmidt, A. Zilberstein, L. Shulman, P. Federman, H. Berissi and M. Revel, FEBS Lett.95, 257 (1978).

    Article  CAS  PubMed  Google Scholar 

  12. G. C. Sen, S. Shaila, B. Lebleu, G. E. Brown, R. C. DesRosiers and P. Lengyel, J. Virol21, 69 (1977).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. S. I. Koliais and N. J. Dimmock, J. gen. Virol.20, 1 (1973).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koliais, S.I. Presence of double stranded regions of viral RNA in infected cells. Experientia 37, 971–972 (1981). https://doi.org/10.1007/BF01971785

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01971785

Keywords

Navigation