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Tonsil surface and core cultures in recurrent tonsillitis: Prevalence of anaerobes and beta-lactamase producing organisms

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Abstract

The bacterial flora of the tonsil surface and core was compared in patients suffering from recurrent tonsillitis. Surface swabs and tonsil core tissues were received as paired samples from 50 patients admitted for elective tonsillectomy. Analysis of paired samples from individual patients revealed differences in the bacterial flora of the tonsil core and the tonsil surface. Of 366 aerobic isolates, 30 % grew from the surface alone, 26 % from the core only and 44 % from both sites. Of 290 anaerobic isolates, 35 % grew from the surface alone, 33 % from the core only and 31 % from both sites. The total number of isolates from surface and core samples was similar (average 9.2 and 8.8, respectively). The range of species isolated was also similar for both surface and core samples, as was the proportion of organisms producing beta-lactamase from each site (10.7 % and 9.5 %, respectively). Eighty-two percent of patients carried beta-lactamase-producing organisms on either the tonsil surface or in the core tissue. A surface swab does not reliably reflect the types of organisms present in the tonsil core in individual patients. Anaerobes are a major component of tonsil surface and core bacterial flora in patients with recurrent tonsillitis. The high carriage rate of beta-lactamase-producing organisms in the tonsils should be considered when selecting antimicrobial therapy for persistent or recurrent tonsillitis.

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Authors and Affiliations

  1. Department of Medical Microbiology, St. Bartholomew's Hospital, West Smithfield, EC1A 7BE, London, UK

    I. J. Mitchelmore, A. J. Hay & S. Tabaqchali

  2. Ear, Nose and Throat Department, St. Bartholomew's Hospital, West Smithfield, EC1A 7BE, London, UK

    P. G. Reilly

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  1. I. J. Mitchelmore
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  2. P. G. Reilly
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  3. A. J. Hay
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  4. S. Tabaqchali
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Mitchelmore, I.J., Reilly, P.G., Hay, A.J. et al. Tonsil surface and core cultures in recurrent tonsillitis: Prevalence of anaerobes and beta-lactamase producing organisms. Eur. J. Clin. Microbiol. Infect. Dis. 13, 542–548 (1994). https://doi.org/10.1007/BF01971304

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