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, Volume 19, Issue 5–6, pp 349–350 | Cite as

Stimulatory effect of hr tumor necrosis factor on TxB2 release by polymorphonuclears and macrophages

  • M. G. Cifone
  • E. Alesse
  • M. Reale
  • M. Bologna
  • P. U. Angeletti
  • P. Conti
General Inflammation

Keywords

Tumor Necrosis Tumor Necrosis Factor TxB2 Release 

References

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    L. Helson, S. Green, A. Carswell and L. J. Old,Effect of tumor necrosis factor on cultured human melanoma cells. Nature (London)258, 731–732 (1975).Google Scholar
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    S. Green, M. A. Chiasson and R. G. Shah,Evidence for the presence of an antitumor factor in serum of normal animals. Cancer Lett.,6, 235–240 (1979).PubMedGoogle Scholar
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    B. D. Williamson, E. A. Carswell, B. Y. Rubin, J. S. Prendergast and L. J. Old,Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon. Proc. nat. Acad. Sci. (Wash.)80, 5397–5401 (1983).Google Scholar
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    D. Pennica, G. E. Nedwin, J. S. Hayflick, P. H. Seeburg, R. Derynck, M. A. Palladino, W. J. Kohr, B. B. Aggarwal and D. V. Goeddel,Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature312, 724–729 (1984).CrossRefPubMedGoogle Scholar
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    P. Conti, M. Allegretta, T. Williams, M. G. Cifone, E. Alesse, M. Reale, E. Boidi and P. A. Dempsey,Enhanced thromboxane synthesis and vacuolization in human polymorphonuclear leukocytes induced by human lymphokine containing supernatants. Clin. Rheumatol.4, n. 4, 410–419 (1985).PubMedGoogle Scholar
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    A. Boyum,Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest.21 (Suppl. 97) 77–89 (1968).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1986

Authors and Affiliations

  • M. G. Cifone
    • 1
  • E. Alesse
    • 1
  • M. Reale
    • 2
  • M. Bologna
    • 1
  • P. U. Angeletti
    • 1
  • P. Conti
    • 2
  1. 1.Cattedra di Patologia Gen., Dip. Scienze BiomedicheUniv. L'AquilaL'AquilaItaly
  2. 2.Cattedra di Immunologia, 1st. Med. Sper.Univ. ChietiChietiItaly

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