, Volume 39, Issue 6, pp 620–622 | Cite as

Influence of the route of administration on thyrotropin-releasing hormone concentration in the mouse brain

  • T. Mitsuma
  • T. Nogimori


TRH penetrates the mouse brain after i.v., i.p., i.m., oral or rectal administration. Except when TRH is administered orally, the penetration rate is about 0.2% of the total dose administered. Higher TRH contents are reached after rectal or i.m. administration.


Total Dose Mouse Brain Hormone Concentration Penetration Rate Rectal Administration 
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Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • T. Mitsuma
    • 1
  • T. Nogimori
    • 1
  1. 1.The 4th Department of Internal MedicineAichi Medical UniversityNagakute, AichiJapan

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