, Volume 39, Issue 6, pp 593–594 | Cite as

Styrene oxidation to styrene oxide in human erythrocytes is catalyzed by oxyhemoglobin

  • F. Tursi
  • M. Samaia
  • M. Salmona
  • G. Belvedere


Oxygenated human erythrocytes catalyzed the oxidation of styrene to styrene oxide. This reaction was inhibited by CO but not by superoxide dismutase, catalase and scavengers of hydroxyl radicals. In partially deoxygenated erythrocytes styrene oxidation showed a linear relationship with the molar fraction of oxyhemoglobin. These data indicate that oxyhemoglobin and not free oxygen radicals are involved in styrene oxidation.


Oxidation Oxygen Hydroxyl Superoxide Linear Relationship 
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Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • F. Tursi
    • 1
    • 2
  • M. Samaia
    • 1
    • 2
  • M. Salmona
    • 1
    • 2
  • G. Belvedere
    • 1
    • 2
  1. 1.Istituto di Ricerche Farmacologiche ‘Mario Negri’MilanItaly
  2. 2.Cattedra Chimica Biologica Istituto Scienze BiomedicheOspedale S. RaffaeleMilanItaly

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