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In vitro activity of vancomycin and teicoplanin againstStaphylococcus aureus andStaphylococcus epidermidis colonizing catheters

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Abstract

In a quantitative in vitro model the activity of vancomycin and teicoplanin in two concentrations (4×MBC and 1 mg/l) againstStaphylococcus aureus and a slime-producingStaphylococcus epidermidis strain colonizing the internal surface of polyurethane and silicone catheters was studied. In comparison with vancomycin, teicoplanin achieved a significantly greater reduction (p<0.05) in the counts ofStaphylococcus aureus andStaphylococcus epidermidis adhering to both polyurethane and silicone catheters.

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Authors and Affiliations

  1. Institute for Environmental Medicine and Hospital Epidemiology, University Hospital of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany

    A. Kropec, J. Huebner, M. Wursthorn & F. D. Daschner

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  1. A. Kropec
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  2. J. Huebner
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  3. M. Wursthorn
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  4. F. D. Daschner
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Kropec, A., Huebner, J., Wursthorn, M. et al. In vitro activity of vancomycin and teicoplanin againstStaphylococcus aureus andStaphylococcus epidermidis colonizing catheters. Eur. J. Clin. Microbiol. Infect. Dis. 12, 545–548 (1993). https://doi.org/10.1007/BF01970962

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  • DOI: https://doi.org/10.1007/BF01970962

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