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Pharmaceutisch Weekblad

, Volume 12, Issue 2, pp 41–45 | Cite as

Opioid receptors and pain

  • R. Dirksen
Review Articles

Abstract

A receptor site is considered to be a transducing factor for effect of the natural ligand. Endorphins and the drugs that mimic their effects (the opiates) are important for analgesia, and consequently the receptor sites involved in actions of opioid drugs are to be considered as relevant to the transmission of pain. The present review describes the distribution of the opioid receptor sites in the central nervous system, and links their presence to pain-specific areas of the central nervous system.

Keywords

Central nervous system Nociceptors Opioids Pain Receptors 

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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1990

Authors and Affiliations

  • R. Dirksen
    • 1
  1. 1.Institute for AnaesthesiologyUniversity of NijmegenHB NijmegenThe Netherlands

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