Summary
Syrian golden hamsters can ‘recover’ from single diabetogenic doses of alloxan and return to normoglycemia. Induction of chronic diabetes was accomplished by multiple injections of streptozotocin.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
P.F. Nace, E.L. House and J.P. Tassoni, Endocrinology58, 305 (1956).
B.P. Neri and C.S. Frings, Clin. Chem.19, 1201 (1973).
A.A. Rossini, A.A. Like, W.L. Chick, M.C. Appel and G.F. Cahill, Proc. natl Acad. Sci. USA74, 2485 (1977).
E.L. House and J.P. Tassoni, Endocrinology61, 309 (1957).
M.F. Sak and S.B. Beaser, Lab. Invest.11, 255 (1962).
Author information
Authors and Affiliations
Additional information
Acknowledgment. This investigation was supported by the National Institutes of Health grant number AM 21186. This work was completed with the excellent technical assistance of Jodi Booth and Mary Goyette. The author wishes to express his appreciation to Marcia Olson for her excellent secretarial assistance in the preparation of this manuscript.
Rights and permissions
About this article
Cite this article
Phares, C.K. Streptozotocin-induced diabetes in Syrian hamsters: New model of diabetes mellitus. Experientia 36, 681–682 (1980). https://doi.org/10.1007/BF01970137
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01970137