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Experientia

, Volume 36, Issue 11, pp 1309–1310 | Cite as

Effect of chronic administration of morphine on primary immune response in mice

  • M. Güngör
  • E. Genç
  • H. Saĝduyu
  • L. Eroĝlu
  • H. Koyuncuoĝlu
Article

Summary

The effect of 3 different doses of chronically-administered morphine on the primary immune response was studied in mice by estimating spleen/body weight ratio and serum hemolysin production against sheep red blood cells (SRBC). It was observed that morphine exerted a dose-dependent inhibitory effect on the immune response which was antagonized by the concomitant administration of naloxone. The findings suggest that the inhibitory effect of morphine is specific.

Keywords

Immune Response Blood Cell Morphine Weight Ratio Naloxone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • M. Güngör
    • 1
  • E. Genç
    • 1
  • H. Saĝduyu
    • 1
  • L. Eroĝlu
    • 1
  • H. Koyuncuoĝlu
    • 1
  1. 1.Department of Pharmacology and Clinical Pharmacology, Istanbul Medical FacultyIstanbul UniversityIstanbul(Turkey)

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