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Ca2+ uptake and distribution in alloxan-diabetic rat arterial and venous smooth muscle

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Summary

This report demonstrates that in experimental diabetes mellitus (DM) calcium uptake and its distribution is altered in rat aortic but not in portal venous smooth muscle. Results are interpreted as consequences of increased calcium binding by aortic smooth muscle in experimental DM, which could account for the hyporeactivity of alloxan diabetic rat aorta reported previously.

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Authors and Affiliations

  1. Downstate Medical Center, Department of Physiology, State University of New York, 450 Clarkson Avenue, Box 31, 11203, Brooklyn, New York, USA

    P. D. M. V. Turlapaty, B. T. Altura & B. M. Altura

Authors
  1. P. D. M. V. Turlapaty
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  2. B. T. Altura
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  3. B. M. Altura
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Additional information

Supported by NIH grant No.HL-18015 and NIDA grant No. DA-02339.

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Turlapaty, P.D.M.V., Altura, B.T. & Altura, B.M. Ca2+ uptake and distribution in alloxan-diabetic rat arterial and venous smooth muscle. Experientia 36, 1298–1299 (1980). https://doi.org/10.1007/BF01969599

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