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, Volume 25, Issue 1–2, pp 63–70 | Cite as

Studies on carbohydrate moieties of glycoproteins in established adjuvant induced arthritis

  • G. Kesava Reddy
  • S. C. Dhar
Immunosuppression and Inflammations

Abstract

The investigation presents the metabolic changes in the carbohydrate components of glycoproteins in several tissues of adjuvant arthritic rats. The experimental arthritis induces a significant modification of total carbohydrate moieties of glycoproteins in arthritic tissues. In both acute and chronic phases of the disease, the adjuvant arthritis caused a significant increase in the levels of carbohydrate moieties of tissue glycoproteins viz. total hexose, hexosamine, fucose, sialic acid, total neutral sugar content and neutral sugar monosaccharides. In addition, the urinary excretions of hexosamine and uronic acid in arthritic rats were found to be elevated significantly. The data from the investigation clearly indicate that the experimental arthritis induces an increased glycoprotein synthesis in most of the tissues examined.

Keywords

Sialic Acid Monosaccharide Hexose Fucose Uronic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1988

Authors and Affiliations

  • G. Kesava Reddy
    • 1
  • S. C. Dhar
    • 1
  1. 1.Department of BiochemistryCentral Leather Research InstituteAdyarIndia

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