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, Volume 30, Issue 1–2, pp 234–236 | Cite as

Histamine metabolism in lungs of rats infected withNippostrongylus brasiliensis

  • J. Dastych
  • J. Wyczółkowska
Histamine: Metabolism and Cell Proliferation


Several parameters connected to histamine metabolism and mast cell number were examined in the lungs of rats infected with the nematodeNippostrongylus brasiliensis. Histamine levels as well as mast cell numbers were found to be increased on day 14 after infection and were elevated during the whole time of the experiment. Histidine decarboxylase activity also reached a peak on day 14. There was no measurable activity of diamine oxidase in the lungs of parasitized and normal rats. It is postulated that the increase in histidine decarboxylase activity and histamine concentration observed in the present study is related to the process of mastocytosis.


Mast Cell Histamine Histidine Diamine Measurable Activity 
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Copyright information

© Birkhäuser Verlag 1990

Authors and Affiliations

  • J. Dastych
    • 1
  • J. Wyczółkowska
    • 1
  1. 1.Department of Biogenic AminesPolish Academy of SciencesŁódźPoland

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