Summary
Endotoxin treated with chromium chloride is less toxic to mice than the parent molecule, but can disrupt intestinal permeability barriers and has an enhanced ability to activate Hageman factor.
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We wish to thank Drs M.W. Brightman and T.S. Reese from the Department of Neurocytology, National Institutes of Health for the use of their Balzers freeze-fracture instrument.
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Walker, R.I., Porvaznik, M., Egan, J.E. et al. Hageman factor activation and tight junction disruption in mice challenged with attenuated endotoxin. Experientia 35, 759–762 (1979). https://doi.org/10.1007/BF01968230
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DOI: https://doi.org/10.1007/BF01968230