, Volume 35, Issue 6, pp 759–762 | Cite as

Hageman factor activation and tight junction disruption in mice challenged with attenuated endotoxin

  • R. I. Walker
  • M. Porvaznik
  • June E. Egan
  • A. M. Miller


Endotoxin treated with chromium chloride is less toxic to mice than the parent molecule, but can disrupt intestinal permeability barriers and has an enhanced ability to activate Hageman factor.


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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • R. I. Walker
    • 1
    • 2
  • M. Porvaznik
    • 1
    • 2
  • June E. Egan
    • 1
    • 2
  • A. M. Miller
    • 1
    • 2
  1. 1.Experimental Hematology DepartmentArmed Forces Radiobiology Research InstituteBethesdaUSA
  2. 2.Veterinary Medicine DepartmentArmed Forces Radiobiology Research InstituteBethesdaUSA

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