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Association of penicillin-tolerant streptococci with epidemics of streptococcal pharyngitis in closed communities

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Abstract

The association of penicillin-tolerant streptococci with reported epidemics of streptococcal pharyngitis in Israel was studied. The streptococcal strains had been isolated during 11 epidemics of community-acquired pharyngitis and 6 food-borne epidemics of pharyngitis occurring in the last 15 years. Strains were stocked lyophilized. Isolates were defined as tolerant if the MBC/MIC ratio for penicillin was ⩾32. All 122 group A streptococcal strains isolated during the epidemics of community-acquired infection showed tolerance to penicillin. In contrast, none of the 52 strains from food-borne epidemics (24 group A, 18 group C and 8 group G) was tolerant.

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References

  1. Dagan, R., Ferne, M., Sheinis, M., Alkan, M., Katzenelson, E. An epidemic of penicillin tolerant group A streptococcal pharyngitis in children living in a closed community (Kibbutz). Journal of Infectious Diseases 1987, 156: 514–516.

    PubMed  Google Scholar 

  2. Ferne, M., Fleiderman, S., Rouach, Z. M., Cohen, D. I., Dinari, G., Bergner-Rabinowitz, S. An outbreak of pharyngitis due to group C beta-hemolytic streptococci in a military camp. In: Levy, E. (ed.): Advances in Pathology. Pergamon Press, Oxford, 1982, p. 65–68.

    Google Scholar 

  3. Michel, J., Ferne, M., Elbaz, L., Michel, N.: Failed antibiotic therapy of follicular tonsillitis related to tolerant strains ofStreptococcus pyogenes. In: Kimura, Y., Kotami, S., Shiokawa (ed.): Recent advances in streptococci and streptococcal diseases. London, 1985, p. 308–309.

  4. Goessens, W. H. F., Pontjne, P., Van Raffe, M., Michel, M. F. Tolerance percentage as a criterion for detection of tolerantStaphylococcus aureus strains. Antimicrobial Agents and Chemotherapy 1984, 25: 575–578.

    PubMed  Google Scholar 

  5. Kim, K. S., Kaplan, E. L. Association of penicillin tolerance with failure to eradicate group A streptococci from patients with pharyngitis. Journal of Pediatrics 1985, 10: 681–684.

    Google Scholar 

  6. Grahn, E., Holm, S. E., Roos, K. Penicillin tolerance in beta-streptococci isolated from patients with tonsillitis. Scandinavian Journal of Infectious Diseases 1987, 19: 421–426.

    PubMed  Google Scholar 

  7. Smith, T. D., Huskins, C. W., Kim, K. S., Kaplan, E. D. Efficacy of beta-lactamase resistant penicillin and influence of penicillin tolerance in eradicating streptococci from the pharynx after failure of penicillin therapy for group A streptococcal pharyngitis. Journal of Pediatrics 1987, 110: 777–782.

    PubMed  Google Scholar 

  8. Feldman, S., Bisno, A. L., Lott, L., Dodge, R., Jackson, R. E. Efficacy of benzanthine penicilline G in group A streptococcal pharyngitis: reevaluation. Journal of Pediatrics 1987, 110: 783–787.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Pediatric Infectious Disease Unit, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, 84101, Beer-Sheva, Israel

    R. Dagan

  2. Ministry of Health, National Streptococcal Reference Center, 86 Jaffa Str., Jerusalem, Israel

    M. Ferne

Authors
  1. R. Dagan
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  2. M. Ferne
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Dagan, R., Ferne, M. Association of penicillin-tolerant streptococci with epidemics of streptococcal pharyngitis in closed communities. Eur. J. Clin. Microbiol. Infect. Dis. 8, 629–631 (1989). https://doi.org/10.1007/BF01968144

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