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Lipase versus teichoic acid and alpha-toxin as antigen in an enzyme immunoassay for serological diagnosis ofStaphylococcus aureus infections

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Abstract

Titres of IgG antibodies toStaphylococcus aureus lipase were analysed in 448 sera from patients suspected of havingStaphylococcus aureus infections and the results compared to those for the routinely used staphylococcal antigens teichoic acid and alpha-toxin. The results indicated that determination of serum antibodies to lipase is a sensitive assay for serological diagnosis of staphylococcal infections and increased sensitivity may be achieved by selection of optimal antigen combinations.

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References

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Authors and Affiliations

  1. Department of Bacteriology, National Institute of Hygiene, ul. Chocimska 24, 00-791, Warsaw, Poland

    S. Tyski & W. Hryniewicz

  2. Department of Bacteriology, Karolinska Institute, S-104 01, Stockholm, Sweden

    P. Colque-Navarro & R. Möllby

  3. Department of Clinical Microbiology, Karolinska Hospital, Box 60500, S-104 01, Stockholm, Sweden

    M. Granström

  4. Departments of Bacteriology and Vaccine Production, National Bacteriological Laboratory, S-105 21, Stockholm, Sweden

    M. Granström & R. Möllby

Authors
  1. S. Tyski
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  2. P. Colque-Navarro
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  3. W. Hryniewicz
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  4. M. Granström
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  5. R. Möllby
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Tyski, S., Colque-Navarro, P., Hryniewicz, W. et al. Lipase versus teichoic acid and alpha-toxin as antigen in an enzyme immunoassay for serological diagnosis ofStaphylococcus aureus infections. Eur. J. Clin. Microbiol. Infect. Dis. 10, 447–449 (1991). https://doi.org/10.1007/BF01968027

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  • DOI: https://doi.org/10.1007/BF01968027

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