Experientia

, Volume 37, Issue 7, pp 757–759 | Cite as

Placental and fetal contraindications of dexamethasone administration to pregnant rats

  • D. Garvey
  • Jane Scott
Article

Summary

Dexamethasone (DEXA) given to pregnant rats for either the last 3 or 6 days of gestation lowered placental, fetal body and adrenal weights. Histologically, DEXA-treated placentas appeared smaller than controls and showed signs of necrosis and pyknosis. Treated animals that were permitted to carry their litters to term did not deliver naturally, and most of their fetuses were dead when excised 1 day postmaturely.

Keywords

Dexamethasone Adrenal Weight Dexamethasone Administration Fetal Body 

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Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • D. Garvey
    • 1
  • Jane Scott
    • 1
  1. 1.Department of AnatomyWright State University School of MedicineDaytonUSA

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