Experientia

, Volume 37, Issue 7, pp 737–738 | Cite as

Effect of adrenalectomy on sound-induced seizure susceptibility and intensity in genetically susceptible rats

  • J. W. Dailey
  • P. C. Jobe
Article

Summary

Neither seizure susceptibility nor intensity was altered by sham-operation or by adrenalectomy in adult rats that are genetically susceptible to sound-induced seizures. Thus, sound-induced seizures in genetically susceptible rats are analogous to those in genetically susceptible mice to the extent that removal of the adrenal glands does not alter established seizure characteristics in either species.

Keywords

Adrenal Gland Seizure Susceptibility Susceptible Mouse Seizure Characteristic 

References

  1. 1.
    P.Y. Sze and S.C. Maxson Psychopharmacology45, 79 (1975).Google Scholar
  2. 2.
    S.C. Maxson and P.Y. Sze, Behav. Genet.7, 323 (1977).PubMedGoogle Scholar
  3. 3.
    S.C. Maxson, J.S. Cowen and P.Y. Sze, Pharmac. Biochem. Behav.7, 221 (1977).Google Scholar
  4. 4.
    J.L. Fuller and B.E. Ginsburg, Am. J. Physiol.,176, 367 (1954).PubMedGoogle Scholar
  5. 5.
    P.C. Jobe, in: Pharmacology of Hearing: Experimental and Clinical Bases. Ed. R. D. Brown and E.A. Daigneault. Wiley Interscience, New York, in press (1981).Google Scholar
  6. 6.
    P.C. Jobe, A.L. Picchioni and L. Chin, J. Pharmac. exp. Ther.184, 1 (1973).Google Scholar
  7. 7.
    P.C. Jobe, R.D. Brown and J.W. Dailey, Life Sci.28, 2031 (1981).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • J. W. Dailey
    • 1
  • P. C. Jobe
    • 1
  1. 1.Departments of Pharmacology and PsychiatryLSU Medical Center and Veterans Administration Medical CenterShreveportUSA

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