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Successful treatment of concomitant pulmonary Nocardiosis and aspergillosis in an immunocompromised renal patient

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Abstract

A case is reported of rapid onset concomitant pulmonary infection withNocardia andAspergillus fumigatus in a patient six weeks after the institution of immunosuppressive therapy for renal vasculitis. Pulmonary lesions completely resolved on treatment with a combination of imipenem, cotrimoxazole and a prolonged course of itraconazole.

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References

  1. Carter JM, Green WR, Callender CO, Peters B: Pulmonary cavitation withNocardia andAspergillus in a renal transplant patient. Journal of the National Medical Association 1990, 82: 527–531.

    PubMed  Google Scholar 

  2. Rubinger D, Drukker A, Shvil Y, Kopolovic Y, Friedlaender MM, Shalit M, Popovtzer MM: Combined cyclophosphamide and corticosteroid-induced remission in severe glomerulopathy associated with systemic vasculitis. American Journal of Nephrology 1986, 6: 346–352.

    PubMed  Google Scholar 

  3. Saral R:Candida andAspergillus infections in immunocompromised patients: an overview. Reviews of Infectious Diseases 1991, 13: 487–492.

    PubMed  Google Scholar 

  4. Chapman SW, Wilson JP: Nocardiosis in transplant recipients. Seminars in Respiratory Infections 1990, 5: 74–79.

    PubMed  Google Scholar 

  5. Simpson OL, Stinson EB, Egger MJ, Remington JS: Nocardial infection in the immunocompromised host: a detailed study in a defined population. Reviews of Infectious Diseases 1981, 3: 492–507.

    PubMed  Google Scholar 

  6. Grossman KB, Bragg DG, Armstrong D: Roentgenographic manifestation of pulmonary nocardiosis. American Review of Respiratory Disease 1973, 108: 1444–1448.

    PubMed  Google Scholar 

  7. Khalih AH: Nocardial brain abscess: a case report. Journal of Neurology 1982, 227: 115–120.

    Article  PubMed  Google Scholar 

  8. Gombert ME, Berkowitz LB, Aulicino TM, du Bouchet L: Therapy of pulmonary nocardiosis in immunocompromised mice. Antimicrobial Agents and Chemotherapy 1990, 34: 1766–1768.

    PubMed  Google Scholar 

  9. Krone A, Schaal KP, Brawanski A, Schuknecht B: Nocardial cerebral abscess cured with imipenem/amikacin and enucleation. Neurosurgical Review 1989, 12: 333–340.

    Article  PubMed  Google Scholar 

  10. Gombert ME, du Bouchet L, Aulicino TM, Berkowitz LB: Antimicrobial synergism in the therapy of experimental cerebral nocardiosis. Journal of Antimicrobial Chemotherapy 1989, 24: 39–43.

    PubMed  Google Scholar 

  11. Dewhurst AG, Cooper MJ, Khan SM, Pallet AP, Dathan JR: Invasive aspergillosis in immunosuppressed patients: potential hazard of hospital building work. British Medical Journal 1990, 301: 802–804.

    PubMed  Google Scholar 

  12. Denning DW, Tucker RM, Hanson LH, Stevens DA: Treatment of invasive aspergillosis with itraconazole. American Journal of Medicine 1989, 86: 791–800.

    Article  PubMed  Google Scholar 

  13. Viviani MA, Tortorano AM, Langer M, Almaviva M, Negri C, Cristina S, Scoccia S, de Maria R, Fiocchi R, Ferrazzi P: Experience with itraconazole in cryptococcosis and aspergillosis. Journal of Infection 1989, 18: 151–165.

    PubMed  Google Scholar 

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Holt, R.I.G., Kwan, J.T.C., Sefton, A.M. et al. Successful treatment of concomitant pulmonary Nocardiosis and aspergillosis in an immunocompromised renal patient. Eur. J. Clin. Microbiol. Infect. Dis. 12, 110–112 (1993). https://doi.org/10.1007/BF01967584

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  • DOI: https://doi.org/10.1007/BF01967584

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