References
Jones RN, Barry AL: The antimicrobial activity of A-56268 (TE-031) and roxithromycin (R965) againstLegionella using broth microdilution method. Journal of Antimicrobial Chemotherapy 1987, 19: 841–842.
Hardy DJ, Swanson RN, Rode RA, Marsh K, Shipkowitz NL, Clement JJ: Enhancement of the in vitro and in vivo activity of clarithromycin againstHaemophilus influenzae by 14-hydroxy-clarithromycin, its major metabolite in humans. Antimicrobial Agents and Chemotherapy 1990, 34: 1407–1413.
Fernandes PB, Ramer N, Rode RA, Freiberg LA: Bioassay for A-56268 (TE-031) and identification of its major metabolite, 14-hydroxy-6-0-methyl erythromycin. European Journal of Clinical Microbiology and Infectious Disease 1988, 7: 73–76.
Sawatari K, Ito N, Nagasawa M, Nakasato H, Koga H, Watanabe K, Tanaka H, Fujita K, Shigeno Y, Yamaguchi K, Izumikawa K, Saito A, Hara K: New susceptibility testing medium (B-SYE agar) forLegionella andLegionella-like organisms. Chemotherapy 1984, 32: 718–723.
National Committee for Clinical Laboratory Standards: Approved standard M7-A2. Standard methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 2nd ed. NCCLS, Villanova, PA, 1990.
Barbaree JM, Sanchez A, Sanden GN: Tolerance ofLegionella species to sodium chloride. Current Microbiology 1983, 9: 1–5.
Barker J, Farrell ID: The effect of charcoal on MICs forLegionella. Journal of Antimicrobial Chemotherapy 1986, 17: 127.
Bornstein N, Roudier C, Fleurette J: Determination of the activity on Legionella of eight macrolides and related agents by comparative testing on three media. Journal of Antimicrobial Chemotherapy 1985, 15: 17–22.
Jones RN: A review of cephalosporin metabolism: A lesson to be learned for future chemotherapy. Diagnostic Microbiology and Infectious Disease 1989, 12: 25–31.
Jones RN, Barry AL, andthe Collaborative Antimicrobial Susceptibility Testing Group: Antimicrobial activity and interactions of pefloxacin and its principal metabolites. European Journal of Clinical Microbiology and Infectious Disease 1989, 8: 551–556.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Jones, R.N., Erwin, M.E. & Barrett, M.S. In vitro activity of clarithromycin (TE-031, A-67268) and 14OH-clarithromycin alone and in combination againstLegionella species. Eur. J. Clin. Microbiol. Infect. Dis. 9, 846–848 (1990). https://doi.org/10.1007/BF01967390
Issue Date:
DOI: https://doi.org/10.1007/BF01967390