Agents and Actions

, Volume 23, Issue 1–2, pp 89–90 | Cite as

Cardiovascular response to β-adrenergic and muscarinic cholinergic receptor stimulation deteriorates inBordetella pertussis-vaccinated pigs

  • D. van Heuven-Nolsen
  • P. D. Verdouw
  • D. J. de Wildt
  • F. P. Nijkamp
General Inflammation

Keywords

Cardiovascular Response Receptor Stimulation Cholinergic Receptor Muscarinic Cholinergic Receptor Cholinergic Receptor Stimulation 

References

  1. [1]
    D. J. De Wildt, J. G. Kreeftenberg and F. P. Nijkamp,Severe impairment of cholinergic and adrenergic responsiveness in Bordetella pertussis vaccinated rats, Eur. J. Pharmacol.86, 315–316 (1983).Google Scholar
  2. [2]
    D. J. De Wildt, Y. De Jong, F. P. Nijkamp and J. G. Kreeftenberg,Vascular β-adrenoceptor blocking activity of endotoxin and pertussis toxin from Bordetella pertussis in rats, Eur. J. Pharmacol.127, 205–210 (1986).PubMedGoogle Scholar
  3. [3]
    A. M. Spiegel, P. Gierschik, M. A. Levine and R. W. Downs,Clinical implications of guanine nucleotide-binding proteins as receptor-effector couplers, New Engl. J. Med.312, 26–33 (1985).PubMedGoogle Scholar
  4. [4]
    D. Van Heuven-Nolsen, D. J. De Wildt and F. P. Nijkamp,Disturbed adrenergic regulation of coronary flow in the guinea pig heart after Bordetella pertussis and endotoxin, Agents and Actions17, 405–406 (1985).Google Scholar
  5. [5]
    A. C. Wardlaw and P. Parton,Bordetella pertussis toxins, Pharmacol. Ther.19, 1–54 (1982).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1988

Authors and Affiliations

  • D. van Heuven-Nolsen
    • 1
  • P. D. Verdouw
    • 1
  • D. J. de Wildt
    • 2
  • F. P. Nijkamp
    • 1
  1. 1.Institute for Veterinary Pharmacology, Pharmacy and PharmacologyState University of UtrechtUtrechtThe Netherlands
  2. 2.Laboratory for Experimental Cardiology, ThoraxcenterErasmus University RotterdamRotterdamThe Netherlands

Personalised recommendations