Agents and Actions

, Volume 23, Issue 1–2, pp 32–33 | Cite as

Morphine dependence modifies macrophage eicosanoid release

  • G. R. Elliott
  • M. J. van Batenburg
  • M. R. Dzoljic
Pain and Inflammation


Morphine Eicosanoid Morphine Dependence Eicosanoid Release Macrophage Eicosanoid 


  1. [1]
    J. H. Jaffe,Drug addiction and drug abuse. In:Pharmacological Basis of Therapeutics, VII Edition. (Eds. A. G. Gillman, L. S. Goodman, J. W. Rall and F. Murad) pp. 532–581, Mac-Millan Publ. Comp. N.Y. 1985.Google Scholar
  2. [2]
    E. Tubaro, G. Boreli, C. Croce, G. Cavallo and C. Santiangeli,Effect of morphine on resistance to infection, J. Infect. Dis.148, 656–666 (1983).PubMedGoogle Scholar
  3. [3]
    R. L. Oropeza-Rendon, V. Speth, G. Hiller, K. Weber and H. Fischer,Prostaglandin E 1 reversibly induces morphological changes in macrophages and inhibits phagocytosis, Exp. Cell. Res.119, 365–371 (1979).PubMedGoogle Scholar
  4. [4]
    H. O. J. Collier, D. L. Francis, W. J. McDonald-Gibson, A. C. Roy and S. A. Saeed,Prostaglandins, cyclic AMP and the mechanism of opiate dependence, Life Sci.17, 85–90 (1975).PubMedGoogle Scholar
  5. [5]
    G. R. Elliott, M. J. van Batenburg and M. R. Dzoljic,Enhanced prostaglandin E 2 and thromboxane B 2 release from resident peritoneal macrophages isolated from morphine dependent rats, FEBS Letters217, 6–10 (1987).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1988

Authors and Affiliations

  • G. R. Elliott
    • 1
  • M. J. van Batenburg
    • 1
  • M. R. Dzoljic
    • 1
  1. 1.Department of PharmacologyErasmus University RotterdamRotterdamThe Netherlands

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