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, Volume 15, Issue 1–2, pp 14–15 | Cite as

Anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72–77 evoke thromboxane generation by macrophages

  • H. P. Hartung
  • D. Bitter-Suermann
  • U. Hadding
Phagocyte Signal Recognition


Peptide Thromboxane Synthetic Hexapeptide Thromboxane Generation 


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    J. Morley, M.A. Bray, R.W. Jones, D.H. Nugteren andD.A. van Dorp,Prostaglandin and thromboxane production by human and guinea pig macrophages and leucocytes, Prostaglandins17, 729–736 (1979).PubMedGoogle Scholar
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    S. Meuer, S. Becker, U. Hadding andD. Bitter-Suermann,The anaphylatoxic peptide C3a of guinea pig complement. I. Purification, physicochemical and antigenic properties, Immunobiology154, 135–146 (1978).PubMedGoogle Scholar
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    D. Bitter-Suermann, S. Becker, S. Meuer, H.U. Schorlemmer, U. Hadding andR. Andreatta,Comparative studies on biological effects of the guinea pig complement-peptide C3a and C3a-related synthetic oligopeptides, Mol. Immunol.17, 1257–1261 (1980).PubMedGoogle Scholar
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    S. Meuer, U. Ecker, U. Hadding andD. Bitter-Suermann,Platelet serotonin release by C3a and C5a: two independent pathways of activation. J. Immun.126, 1506–1509 (1981).PubMedGoogle Scholar
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    U. Hadding, H.P. Hartung, H. Rasokat andD. Gemsa,Peritoneal macrophages release prostaglandin E and thromboxane B 2 in response to C3b. Adv. Med. Biol.155, 531–533 (1982).Google Scholar
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    H.P. Hartung, U. Hadding, D. Bitter-Suermann andD. Gemsa,Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. J. Immun.130, 2861–2865 (1983).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1984

Authors and Affiliations

  • H. P. Hartung
    • 1
  • D. Bitter-Suermann
    • 1
  • U. Hadding
    • 1
  1. 1.Institute of Medical MicrobiologyJohannes Gutenberg University MainzMainzW. Germany

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