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Interpretation of visual space under drug-induced ergotropic and trophotropic arousal

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Abstract

It was found that ergotropic arousal inducing drugs, such as psilocybin, a Ditran®-type ‘glycolate’ andd-amphet-amine, significantly lower human spatial distortion thresholds, i.e. these drugs, interfere with counter-adaptation to optical distortion, or the expectation to see the world undistorted. The trophotropic arousal inducing chlorpromazine® on the other hand promotes such counter-adaptation, i.e. the optimization of visual information. Optimization is independent from the rat at which the distorting stimulus is presented.

Optimization is regarded here as a cortical (perceptual-behavioral) interpretive process while interference with and promotion of the optimization are subcortical influences.

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Authors and Affiliations

  1. College of Optometry and Departments of Psychiatry and Pharmacology, College of Medicine, The Ohio State University, 43210, Columbus, Ohio

    Richard M. Hill & Roland Fischer

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  1. Richard M. Hill
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  2. Roland Fischer
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Hill, R.M., Fischer, R. Interpretation of visual space under drug-induced ergotropic and trophotropic arousal. Agents and Actions 2, 122–130 (1971). https://doi.org/10.1007/BF01966750

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  • DOI: https://doi.org/10.1007/BF01966750

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