, Volume 41, Issue 4, pp 481–482 | Cite as

Substance P-like immunoreactivity in the frog dorsal root ganglia

  • M. Kemali
  • D. Gioffré
Short Communications


The distribution of substance P-like immunoreactivity was studied in the thoracic dorsal root ganglia of the frogRana esculenta by immunohistochemistry. Substance P-like immunoreactivity was contained in approximately 50% of primary sensory neurons. The immunoreactive fibers arising from the cell bodies are collected in small bundles within the ganglia neuropil before entering the central and peripheral roots.

Key words

Substance P immunohistochemistry spinal ganglia frog 


  1. 1.
    Nicoll, R. A., Schenker, C., and Leeman, S. E., A. Rev. Neurosci.3 (1980) 227.CrossRefGoogle Scholar
  2. 2.
    Chan-Palay, V., and Palay, S. L., Proc. natl. Acad. Sci.74 (1977) 4050.PubMedGoogle Scholar
  3. 3.
    Hökfelt, T., Kellerth, J.-O., Nilsson, G., and Pernow, B., Brain Res.100 (1975) 235.CrossRefPubMedGoogle Scholar
  4. 4.
    Di Figlia, M., Aronin, N., and Leeman, S. E., Neuroscience7 (1982) 1127.CrossRefPubMedGoogle Scholar
  5. 5.
    Inagaki, S., Senba, E., Shiosaka, S., Takagi, H., Kawai, Y., Takatsuki, K., Sakanaka, M., Matsusaki, T., and Tohyama, M., J. comp. Neurol.201 (1981) 243.CrossRefPubMedGoogle Scholar
  6. 6.
    Lorez, H.-P., and Kemali, M., Neurosci. Lett.26 (1981) 119.CrossRefPubMedGoogle Scholar
  7. 7.
    Barber, R. P. Vaughn, J. E., Slemmon, J. R., Salvaterra, P. M., Roberts, E., and Leeman, S. E., J. comp. Neurol.184 (1979) 331.CrossRefPubMedGoogle Scholar
  8. 8.
    Barbut, D., Polak, J. M., and Wall, P. D., Brain Res.205 (1981) 289.CrossRefPubMedGoogle Scholar
  9. 9.
    Jessell, T., Tsunoo, A., Kanazawa, I., and Otsuka, M., Brain Res.168 (1979) 247.CrossRefPubMedGoogle Scholar
  10. 10.
    Takahashi, T., and Otsuka, M., Brain Res.87 (1975) 1.CrossRefPubMedGoogle Scholar
  11. 11.
    Otsuka, M., and Konishi, S. in: Substance P, p. 207. Eds U. S. von Euler and B. Pernow, Raven Press, New York 1977.Google Scholar
  12. 12.
    Konishi, S., and Otsuka, M., Brain Res.65 (1974) 397.CrossRefPubMedGoogle Scholar
  13. 13.
    Sternberger, L. A., Immunocytochemistry. Prentice-Hall Inc., Englewood Cliffs, NJ 1974.Google Scholar
  14. 14.
    Wilhelm, G. B., and Coggeshall, R. E., J. comp. Neurol.196 (1981). 421.CrossRefPubMedGoogle Scholar
  15. 15.
    Pick, J., J. comp. Neurol.107 (1957) 169.CrossRefPubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • M. Kemali
    • 1
  • D. Gioffré
    • 1
  1. 1.Istituto Cibernetica, CNRNaples(Italy)

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