Skip to main content
SpringerLink
Log in

Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain

  • Short Communications
  • Published:
Experientia Aims and scope Submit manuscript

Summary

The rate of tryptophan hydroxylation in vivo is unaltered in brain areas of 5, 9 and 21 week-old Lyon genetically Hypertensive (LH) rats as compared to both Lyon Normotensive (LN) and Low Blood Pressure (LL) rats, except for a decrease in the C1 area of the medulla oblongata in 9 week-old animals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Vincent, M., Dupont, J., and Sassard, J., Jap. Heart J.20 (1979) 135.

    Google Scholar 

  2. Kuhn, D. M., Wolf, B. A., and Lovenberg, W., Hypertension2 (1980) 243.

    Article  CAS  PubMed  Google Scholar 

  3. Herr, B. E., Gallager, D. W., and Roth, R. H., Biochem. Pharmac.24 (1975) 2019.

    Article  CAS  Google Scholar 

  4. Tappaz, M. L., and Pujol, J. F., J. Neurochem.34 (1980) 933.

    Article  CAS  PubMed  Google Scholar 

  5. Carlsson, A., Davis, J. N., Kehr, W., Lindqvist, M., and Atack, C. V., Naunyn-Schmiedebergs Arch. Pharmak.275 (1972) 153.

    Article  CAS  Google Scholar 

  6. Palkovits, M., Brain Res.59 (1973) 449.

    Article  CAS  PubMed  Google Scholar 

  7. Dahlström, A., and Fuxe, K., Acta physiol. scand.62 (1964) 1.

    Google Scholar 

  8. Hökfelt, T., Fuxe, K., Goldstein, M., and Johansson, O., Brain Res.66 (1974) 235.

    Article  Google Scholar 

  9. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. biol. Chem.193 (1951) 265.

    Article  CAS  PubMed  Google Scholar 

  10. Smith, M. L., Browning, R. A., and Meyers, J. H., Eur. J. Pharmac.53 (1979) 301.

    Article  CAS  Google Scholar 

  11. Howe, P. R. C., Stead, B. H., and Chalmers, J. P., in: Hypertensive Mechanisms, p. 627. Eds W. Rascher, D. Clough and D. Ganten. Schattauer, Stuttgart 1982.

    Google Scholar 

  12. Howe, P. R. C., Kuhn, D. M., Minson, J. B., Stead, B. H., and Chalmers, J. P., Brain Res.270 (1983) 29.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Département de Physiologie et Pharmacologie Clinique, ERA CNRS 894, Faculté de Pharmacie, avenue Rockefeller, F-69373, Lyon Cédex 08, France

    L. Denoroy, M. L. Tappaz, R. Fety, M. Vincent, B. Renaud & J. Sassard

  2. Groupe de Neurochimie Fonctionnelle, INSERM U 171, avenue Rockefeller, F-69373, Lyon Cédex 08, France

    L. Denoroy, M. L. Tappaz, R. Fety, M. Vincent, B. Renaud & J. Sassard

  3. Laboratoire de Physiologie, Faculté de Médecine Grange Blanche, 8, avenue Rockefeller, F-69373, Lyon Cédex 08, France

    L. Denoroy, M. L. Tappaz, R. Fety, M. Vincent, B. Renaud & J. Sassard

Authors
  1. L. Denoroy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. L. Tappaz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Fety
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Vincent
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. B. Renaud
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Sassard
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Acknowledgment. The authors wish to thank Dr M.F. Belin, Dr J.F. Pujol and Mrs J. Sacquet for their help during this study. This work was supported by the Fondation pour la Recherche Médicale Française and the C.N.R.S.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Denoroy, L., Tappaz, M.L., Fety, R. et al. Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain. Experientia 41, 478–479 (1985). https://doi.org/10.1007/BF01966156

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01966156

Key words

Search

Navigation