, Volume 36, Issue 9, pp 1127–1128 | Cite as

Plasma cyclic 3′,5′-guanosine monophosphate and cyclic 3′,5′-adenosine monophosphate response to methacholine in man

  • S. Hata
  • F. Okada
  • M. Honma
  • M. Ui


Cholinergic agents are known to induce increases in tissue and plasma levels of cyclic GMP in experimental animals. We observed that i.m. injection of methacholine, a cholinergic agent, caused significant increases in plasma cyclic GMP and cyclic AMP in man.


Adenosine Experimental Animal Plasma Level Monophosphate Guanosine 
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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • S. Hata
    • 1
  • F. Okada
    • 1
  • M. Honma
    • 1
  • M. Ui
    • 1
  1. 1.The Second Department of Internal Medicine, School of Medicine, Department of Psychiatry and Neurology, and Physiological Chemistry, Faculty of Pharmaceutical SciencesHokkaido UniversitySapporoJapan

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