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Effects of a mammalian cholesterol biosynthesis inhibitor on adipocyte ultrastructure and metamorphosis inRhodnius prolixus (Hemiptera)

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Summary

A potent inhibitor of cholesterol biosynthesis in rodents [BMVA; 5-(4-biphenylyl)-3-methylvaleric acid] inhibits metamorphosis of 4th stage larvae of the blood-sucking bugRhodnius prolixus.

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Authors and Affiliations

  1. Warner-Lambert Pharmaceutical Research Division, Department of Toxicology, 48105, Ann Arbor, Michigan, USA

    E. J. McGuire, J. E. J. Habowsky & F. A. de la Iglesia

  2. Department of Biology, University of Windsor, Windsor, Ontario, Canada

    E. J. McGuire, J. E. J. Habowsky & F. A. de la Iglesia

Authors
  1. E. J. McGuire
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  2. J. E. J. Habowsky
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  3. F. A. de la Iglesia
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Additional information

This work was supported in part by grants from the National Research Council of Canada awarded to Warner-Lambert Research Institute, Mississauga, Ontario.

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McGuire, E.J., Habowsky, J.E.J. & de la Iglesia, F.A. Effects of a mammalian cholesterol biosynthesis inhibitor on adipocyte ultrastructure and metamorphosis inRhodnius prolixus (Hemiptera). Experientia 36, 1099–1101 (1980). https://doi.org/10.1007/BF01965992

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